Neonatal sepsis markers used at Portoviejo General Hospital
DOI:
https://doi.org/10.5281/zenodo.14629885Keywords:
sepsis markers, procalcitonin, C-reactive protein, neonatal sepsisAbstract
Neonatal sepsis is an invasive infectious disease that affects children under 28 days of age and is characterized by potentially fatal organ dysfunction due to the dysregulation of the neonate's response to invasive microorganisms. It is classified into early sepsis, manifested within the first 72 hours of life, and late sepsis, occurring after this period, representing a significant cause of morbidity and mortality in this population. The objective was to evaluate the sepsis markers used at the General Hospital of Portoviejo. The qualitative-quantitative, descriptive, cross-sectional, and retrospective observational study included 42 reports of neonatal sepsis markers obtained from anonymized medical records of newborns diagnosed with sepsis between July and December 2022. Descriptive statistics and the Pearson coefficient were applied to analyze the correlation between variables. Most cases involved male neonates, full-term births, children of mothers aged 26 to 35 years, and those from rural areas. Late sepsis predominated, and procalcitonin was the most sensitive marker, with elevated levels in all cases. A significant relationship was found between procalcitonin and the diagnosis of sepsis, the medical history or risk factors, and respiratory distress as a clinical manifestation.
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Data Availability Statement
The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
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Copyright (c) 2025 Ginger L. Mero, Yaritza M. Moreira, Nancy Toledo (Author)
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