Physical and chemical properties of chitosan salts obtained from common lobster chitin (Panulirus argus)
DOI:
https://doi.org/10.5281/zenodo.13996969Keywords:
chitosan salts, physical and chemical properties, spray drying, powder propertiesAbstract
The physical and chemical properties of chitosan salts were evaluated. To produce chitosan acetate and lactate, chitosan solutions at 4% (w/v) were prepared in solutions of acetic and lactic acids at 10% (v/v), respectively. The spray drying was carried out at inlet/outlet temperatures of 160/100 ºC. The particle size, shape, surface morphology, and microstructure of the chitosan salts were characterized. Additionally, moisture content and water activity were determined. Analyses of the chemical structure and thermal properties of the compounds were performed. The color of the chitosan and its salts-forming solutions (FPS) was also evaluated. Chitosan lactate exhibited more spherical particles than chitosan acetate, which showed greater particle agglomeration with irregular and sticky shapes, associated with its higher moisture content. Chitosan acetate proved more stable, exhibiting a higher exothermic temperature than chitosan lactate. A partial conversion of the chitosan acetate structure was observed due to the high temperature of the spray drying process. The FPS of chitosan lactate was the least luminous and showed the highest b* value (p≤0.05), indicating a more intense coloration. No significant differences were found in the values for a* component between the FPS of chitosan and its salts.
References
Aranaz, I., Alcántara, A.R., Civera, M.C., Arias, C., Elorza, B., Heras, A., & Acosta, N. (2021). Chitosan: An Overview of Its Properties and Applications. Polymers (Basel), 3(19), 3256. https://doi.org/10.3390/polym13193256
Casariego, A., Souza, W.S., Cerqueira, M.A., Texeira, J.A., Cruz, L., Díaz, R., & Vicente, A. (2009) A. Chitosan/clay film´s properties as affected by biopolymers and clay micro/nanoparticles´s concentrations. Food Hydrocolloids, 23, 1895-1902.
Cervera, M.F., Heinämäki, J., de la Paz, N., López, O., Maunu, S.L., Virtanen, T., Hatanpää, T., Antikainen, O., Nogueira, A., Fundora, J., & Yliruusi, J. (2011). Effects of spray drying on physicochemical properties of chitosan acid salts. AAPS PharmSciTech, 12(2), 637-649. https://doi.org/10.1208/s12249-011-9620-3
Chaudhary, P., Janmeda, P., Docea, A.O., Yeskaliyeva, B., Abdull, A.F., Modu, B., Calina, D., & Sharifi-Rad, J. (2023). Oxidative stress, free radicals and antioxidants: potential crosstalk in the pathophysiology of human diseases. Frontiers in Chemistry, 11, 1158198. https://doi.org/10.3389/fchem.2023.1158198
de la Paz, N., Fernández, M., López, O., García, C., Nogueira, A., Torres, L., Turiño, W., & Heinämäki, J. (2021). Spray drying of chitosan acid salts: process development, scaling up and physicochemical material characterization. Marine Drugs, 19(6), 329. https://doi.org/10.3390/md19060329
Demarger-Andre, S., & Domard, A. (1994). Chitosan carboxylic acid salts in solution and the solid state. Carbohydrate Polymers, 23(3), 211-219. https://doi.org/10.1016/0144-8617(94)90104-X
Desai, N., Rana, D., Salave, S., Gupta, R., Patel, P., Karunakaran, B., Sharma, A., Giri, J., Benival, D., & Kommineni, N. (2023). Chitosan: a potential biopolymer in drug delivery and biomedical applications. Pharmaceutics, 15(4), 1313. https://doi.org/10.3390/pharmaceutics15041313
Di Foggia, M., Tsukada, M., & Taddei, P. (2023). Vibrational study on the structure, bioactivity, and silver adsorption of silk fibroin fibers grafted with methacrylonitrile. Molecules, 28(6), https://doi.org/10.3390/molecules28062551
Elieh-Ali-Komi, D., & Hamblin, M.R. (2016). Chitin and chitosan: production and application of versatile biomedical nanomaterials. International Journal of Advanced Research (Indore), 4(3), 411-427. https://pmc.ncbi.nlm.nih.gov/articles/PMC5094803/
Herdiana, Y., Husni, P., Nurhasanah, S., Shamsuddin, S., & Wathoni, N. (2023). Chitosan-based nano systems for natural antioxidants in breast cancer therapy. Polymers (Basel), 15(13), 2953. https://doi.org/10.3390/polym15132953
Lu, B., Xiao, W.J., & Chen, J.R. (2022). Recent advances in visible-light-mediated amide synthesis. Molecules, 27(2), 517. https://doi.org/10.3390/molecules27020517
Mohan, C.O., Gunasekaran, S., & Ravishankar, C.N. (2019). Chitosan-capped gold nanoparticles for indicating temperature abuse in frozen stored products. NPJ Science of Food, 3, 2. https://doi.org/10.1038/s41538-019-0034-z
Muraleedharan, K., Alikutty, P., Abdul Mujeeb, V.M., & Sarada, K. (2015). Kinetic studies on the thermal dehydration and degradation of chitosan and citralidene chitosan. Journal of Polymers and the Environment, 23, 1-10. https://doi.org/10.1007/s10924-014-0665-8
Nunthanid, J., Huanbutta, K., Luangtana-Anan, M. Sriamornsak, P., Limmatvapirat, S., & Puttipipatkhachorn, S. (2008). Development of time-, pH-, and enzyme-controlled colonic drug delivery using spray-dried chitosan acetate and hydroxypropyl methylcellulose. European Journal of Pharmaceutics and Biopharmaceutics, 68, 253-259. https://doi.org/10.1016/j.ejpb.2007.05.017
Pruteanu, L.L., Bailey, D.S., Grădinaru, A.C., & Jäntschi, L. (2023). The biochemistry and effectiveness of antioxidants in food, fruits, and marine algae. Antioxidants (Basel), 12(4), 860. https://doi.org/10.3390/antiox12040860
Santos, V.P., Marques, N.S.S., Maia, P.C.S.V., Lima, M.A.B., Franco, L.O., & Campos-Takaki, G.M. (2020). Seafood waste as attractive source of chitin and chitosan production and their applications. International Journal of Molecular Sciences, 21(12), 4290. https://doi.org/10.3390/ijms21124290
Teshome, E., Forsido, S.F., Rupasinghe, H.P.V., & Olika, E.K. (2022). Potentials of natural preservatives to enhance food safety and shelf life: a review. Scientific World Journal, 9901018. https://doi.org/10.1155/2022/9901018
Yao, F., Chen, W., Wang, H., Liu, H., Yao, K., & Sun, P. (2003). A study on cytocompatible poly (chitosan-g-L-lactic acid). Polymer, 44, 6435-6441. https://doi.org/10.1016/S0032-3861(03)00676-1
Published
Data Availability Statement
The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
Issue
Section
License
Copyright (c) 2024 Nilia de la Paz, Mirna Fernández, Jarol A. Hernández, Mario A. García (Autor/a)
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
How to Cite
